Ethyl 4-chloro-6-fluoroquinoline-3-carboxylate

Ethyl 4-chloro-6-fluoroquinoline-3-carboxylate - Names and Identifiers

Name	Ethyl 4-chloro-6-fluoroquinoline-3-carboxylate
Synonyms	Ethyl 4-chloro-6-fluoroquinoline-3-carboxylate ethyl 6-chloro-4-fluoroquinoline-3-carboxylate 4-Chloro-6-fluoroquinoline-3-carboxylic acid ethyl ester 3-Quinolinecarboxylicacid, 4-chloro-6-fluoro-, ethyl ester 3-quinolinecarboxylic acid, 4-chloro-6-fluoro-, ethyl ester
CAS	77779-49-8
InChI	InChI=1/C12H9ClFNO2/c1-2-17-12(16)9-6-15-10-4-3-7(14)5-8(10)11(9)13/h3-6H,2H2,1H3

Ethyl 4-chloro-6-fluoroquinoline-3-carboxylate - Physico-chemical Properties

Molecular Formula	C12H9ClFNO2
Molar Mass	253.66
Density	1.354
Melting Point	62-63℃
Boling Point	332.1°C at 760 mmHg
Flash Point	154.6°C
Vapor Presure	0.00015mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.593
MDL	MFCD00173350

Ethyl 4-chloro-6-fluoroquinoline-3-carboxylate - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36 - Irritating to the eyes
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Ethyl 4-chloro-6-fluoroquinoline-3-carboxylate - Introduction

Ethyl is an organic compound with the chemical formula C13H9ClFNO2. The following is a detailed description of its nature, use, formulation and safety information:

Nature:
-Appearance: Colorless to yellow crystal or powdery substance.
-Solubility: Soluble in some organic solvents, such as ethanol, dimethylformamide and dichloromethane.
-Melting point: Its melting point is about 77-80°C.
-preservation: should be stored in a cool and dry place, away from fire and oxidant.

Use:
- Ethyl is an important intermediate compound, which has a wide range of applications in the fields of pharmacy, pesticide and organic chemical synthesis.
-It can be used to synthesize biologically active compounds, such as drugs and pesticides.
-At the same time, it can also be used as a reagent in organic synthesis, used to construct quinoline and esterification reactions.

Preparation Method:
- Ethyl can be prepared by a variety of synthetic methods.
-A commonly used method is to chlorinate and fluorinate quinoline and amino acid ester, and then perform esterification reaction to generate Ethyl.

Safety Information:
- Ethyl is generally relatively safe under normal operating conditions, but the following aspects still need to be paid attention:
-It is a chemical and appropriate protective measures should be taken, such as wearing gloves, goggles and protective clothing.
-Avoid inhaling its dust or gas, avoid direct contact with skin and eyes.
-Need to be stored in a sealed container, away from fire and oxidizing agents.
-When using and handling, please refer to the relevant chemical safety manual and consult professional advice.

Last Update：2024-04-09 21:11:58